Peptide Libraries
At Intavis Peptide Services, we have long-lasting experience with the automated parallel synthesis of peptides. We leverage that knowledge to provide you with peptide libraries according to your needs.
Whether you seek linear, cyclic or other modified peptides, we can provide you with the custom peptide library you need to proceed in your project.
Immunogenicity testing
Peptide/Proteine interaction mapping
T-cell stimulation
Substrate identification
Our offering
We offer customized peptide libraries in a 2μmol synthesis scale in formats of 48 or 96 well plates.
Category A
Crude peptides + MALDI, no precise weighing
Category B
Guaranteed >70% purity + MS and HPLC, no precise weighing
Category C
Guaranteed >70% purity + MS and HPLC, precise weighing
Our service
1. Initial consulting
We will evaluate your peptide library on feasibility and physical properties to ensure high success rates. Also we can support you in designing your peptide libraries according to your research aims.
2. Fast turn-around times
From order to delivery we can be as fast as 4 weeks, depending on the length of peptides, complexity, purity and modifications. You will receive a delivery time estimate with your quote.
3. Continuous Feedback
You will receive regular updates on the status of your peptide library project.
4. CoA and documentation
With your peptide library, you will receive a Certificate of Analysis and the complete analytical documentation, including HPLC and MS traces.
Peptide Libraries Modifications
If you cannot find a modification, please reach out to us. We will make it possible.
| Amino Acid |
|---|
| (L)-Phospho amino acids |
| (D)-Amino acids |
| Heavy isotope amino acids |
| 8-Amino-3,6-dioxaoctanoic acid |
| 6-Aminohexanoic acid |
| 2-Aminobutanoic acid |
| (L)-Lys(Ac)- |
| (L)-Glyco amino acids |
| (L)-Cys(Carboxamidomethyl)- |
| (L)-Arg(Me)2symm. |
| (L)-Arg(Me)2asymm. |
| (L)-Lys(Me)3– |
| (L)-Lys(Me)2– |
| (L)-Lys(Me)1– |
| Citrulline |
| Peptide | N-term |
|---|---|
| 5/6-FITC | ✓ |
| 5-FITC | ✓ |
| 5/6-Tamra | ✓ |
| Biotin | ✓ |
| Dinitrphenyl (DNP) | ✓ |
| Dabsyl (Dabs) | ✓ |
| Dabsyl (Dans) | ✓ |
| Methoxycoumarinacetyl (MCA) | ✓ |
| Maleimidopropionyl- | ✓ |
| Azidohexanoyl- | ✓ |
| Cy-5 | ✓ |
| Dyomics dyes | ✓ |
| Alexa Fluor® dyes | ✓ |
| 5/6-FAM | ✓ |
| 5-FAM | ✓ |
| Sulfated peptides |
Frequently asked Questions
We start to call it libraries from 48 peptides onwards, but this term is a vague definition.
We can essentially any scale in the mg range in library format, but the regular amount would be 1-2 mg per peptide. We use automated synthesizers, that can generate many peptides in parallel in that scale.
Yes, we surely can synthesize peptide libraries with chemical modifications.
Very often, peptides ordered in library formats are used in early discovery stage and thus, very high purities may not be required. They may often be used as crude material without purification or at a guaranteed purity of above 70%. However, also higher purities are possible.
When screening for MHC class I T cell epitopes, often 9-11mer peptides are used, which should be synthesized with a C-terminal acid. For MHC class II T cell epitope and B cell epitope screenings, C-terminal amides work as well and are more robust than acids.
Peptides are delivered as freeze-dried powder in separate vials, except for different arrangements discussed prior to the synthesis.
Yes, we can weigh each individual peptide for you to gain precision.
Order your peptides
Click order and a form will pop-up so you can enter your sequence directly. Alternatively upload a document listing your peptides or conjugates.